Oh, probably eventually, but not permanently.
It’s like any other famous comic book couple than aren’t like Sue Storm and Reed Richards or Lois Lane and Superman: full of enough history that neither character can be separated from the other, but with so much baggage in the way they never last.

If it happens, it’ll either be because the movies get them together, or a writer who read and loved the Bronze Age Avengers wants them back together.
But it’s a cycle. One writer may want them back together–and even succeed, depending on their clout and how long their run goes–but another might hate the idea, or hate one of the characters, or want to use one character but not the other. And then they’ll break up (and then be more afraid of the writer taking a ‘scorched earth’ approach to this than the actual break up).
Honestly I’m fine with that. Such are comics. Most of my favorite comic book couples are done with in much the same way, and it’s just a result of the nature of a medium that has ongoing stories handled by many different creators.
Really what I hope for is they simply have an amicable relationship, with no attempts to diminish their past because someone really wants Wanda to be with Simon, or Vision to be a toaster with no feelings.